Electronic letters

Publications:

Penston JG.
What's really behind the antagonism for the polypill?
BMJ Rapid Response Letters, September 2003.
Reply to: Wald NJ, Law MR. A strategy to reduce cardiovascular disease by more than 80%. BMJ 2003;326;1419-23.

Penston JG.
Let the sun shine in.
BMJ Rapid Response Letters, December 2003
Reply to: Smith R. Editor’s choice: The drugs don’t work. BMJ 2003;327; 13th December.

Penston J.
"Evidence Based" medicine is based on the wrong evidence.
BMJ Rapid Response Letters, May 2004
Reply to: Da Prato RA. “Evidence-based” medicine is based on the wrong evidence. BMJ rapid Response Letters, 16th May 2004.

Penston J.
A reminder of the flaws of PROGRESS.
BMJ Rapid Response Letters, October 2004
Reply to: Wennberg R & Zimmermann C. The PROGRESS trial three years later: time for a balanced report of effectiveness. BMJ 2004;329;968-70.

Penston J.
How much should patients be told about their treatment?
BMJ Rapid Response Letters, December 2004
Reply to: Verma S & Strauss M. Angiotensin receptor blockers and myocardial infarction. BMJ 2004;329;1248-9.

Penston J.
Time for more than tinkering.
BMJ Rapid Response Letters, December 2004
Reply to: Abbasi K & Jones G. Trial protocols at the BMJ. BMJ 2004;329;1360.

Penston J.
Misleading claims - a symptom of even more serious flaws?
BMJ Rapid Response Letters, November 2004
Reply to: Montori VM, Jaeschke R, Schunemann HJ, et al. User’s guide to detecting misleading claims in clinical research reports. BMJ 2004;329;1093-6.

Penston J.
An alternative interpretation of the data.
BMJ Rapid Response Letters, March 2005
Reply to: Leontiadis GI, Sharma VK, Howden CW. Systematic review and meta- analysis of proton pump inhibitor therapy in peptic ulcer bleeding. BMJ 2005;330;568-70.

Penston J.
When meta-analysis and common sense collide.
BMJ Rapid Response Letters, March 2005.
Reply to: Howden CW, Leontiadis GI, Sharma VK. An alternative interpretation of the data. BMJ. Rapid responses, 22nd March 2005.

Penston J.
Composite end-points in clinical trials.
BMJ Rapid Response Letters, March 2005
Reply to: Montori VM, Permanyer-Miralda G, Ferreira-Gonzalez I, Busse JW, Pacheco-Huergo V, et al. Validity of composite end points in clinical trials. BMJ 2005;330;594-6.

Penston J.
Chalk and cheese...
BMJ Rapid Response Letters, April 2005
Reply to: Wei L, Ebrahim S, Bartlett C, Davey PG,et al. Statin use in the secondary prevention of coronary heart disease in primary care: cohort study and comparison of inclusion and outcome with patients in randomised trials. BMJ 2005;330;821-4.

Penston J.
Still chalk and cheese...
BMJ Rapid Response Letters, April 2005
Reply to: Wei L, Ebrahim S, Bartlett C, Davey PG, et al. Statin use in the secondary prevention of coronary heart disease in primary care: cohort study and comparison of inclusion and outcome with patients in randomised trials. BMJ 2005;330;821-4.

Penston J.
Let's be serious...
BMJ Rapid Response Letters, June 2005
Reply to: Moldrup C . No cure, no pay. BMJ 2005;330;1262-4.

Penston J.
The evil of silencing opinion.
BMJ Rapid Response Letters, June 2005
Reply to: Davies S, Delamothe T. Revitalising rapid responses. BMJ 2005;330;1284.

Penston J.
The mythology behind the scare stories.
BMJ Rapid Response Letters, June 2005
Reply to: Hippisley-Cox J, Coupland C. Risk of myocardial infarction in patients taking cyclo-oxygenase-2 inhibitors or conventional non-steroidal anti-inflammatory drugs: population based nested case-control study. BMJ 2005;330;1366-9.

Penston J.
The strange case of the missing premise.
BMJ Rapid Response Letters, June 2005
Reply to: Elwood P, Morgan G, Brown G, Pickering J. For and against: Aspirin for everyone older than fifty? BMJ 2005;330;1440-1.

Penston J.
The root of the problem...
BMJ Rapid Response Letters, July 2005
Reply to: Westin S, Heath I. Thresholds for normal blood pressure and serum cholesterol. BMJ 2005;330;1461-2.

Penston J.
A sufficient reason to avoid SSRIs.
BMJ Rapid Response Letters, September 2005
Reply to: Paton C & Ferrier IN. SSRIs and gastrointestinal bleeding. BMJ 2005;331;529-30.

Penston J.
An asylum of experts.
BMJ Rapid Response Letters, September 2005
Reply to: Getz L, Sigurdsson JA, Hetlevik I, Kirkengen AL, et al. Estimating the high risk group for cardiovascular disease in the Norwegian HUNT 2 population according to the 2003 European guidelines: modelling study. BMJ 2005;331;1551-4.

Penston J.
ARBs and myocardial infarction - the saga continues.
BMJ Rapid Response Letters, October 2005
Reply to: McDonald MA, Simpson SH, Ezekowitz JA, Gyenes G, Tsuyuki RT. Angiotensin receptor blockers and risk of myocardial infarction: systematic review. BMJ doi:10.1136/bmj.38595.518542.3A (29th September 2005)

Penston J.
When all thirty authors are wrong...
BMJ Rapid Response Letters, October 2005
Reply to: Dormandy JA, Charbonnel B, Eckland DJA, Erdmann E, Massi- Benedetti M, et al. Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): a randomised controlled trial. Lancet 2005;366;1279-89.

Penston J.
Folly and naivety.
BMJ Rapid Response Letters, November 2005
Reply to: Shaw JM, Mynors G, Kelham C. Information for patients on medicines. BMJ 2005;331;1034-5.

Penston J.
The unpalatable truth for nurse practitioners.
BMJ Rapid Response Letters, December 2005
Reply to: Young G. The nursing profession’s coming of age. BMJ 2005;331;1415.

Penston J.
A marketing ploy in the guise of clinical research?
BMJ Rapid Response Letters, February 2006
Reply to: Lane JA, Noble S, Donovan JL, Murray LJ, Egger M, et al. Impact of Helicobacter pylori eradication on dyspepsia, health resource use, and quality of life in the Bristol helicobacter project: randomised controlled trial. BMJ 2006;332;199-202.

Penston J.
A marketing ploy in the guise of clinical research? –further comments.
BMJ Rapid Response Letters, March 2006
Reply to: Lane JA, Egger M, Harvey IM, et al. The impact of H. pylori eradication on dyspepsia, health resource use and quality of life in the Bristol Helicobacter Project. Authors’ reply. BMJ, rapid response letters 24th February 2006. BMJ 2006;332;199-202.

Penston J.
When there’s no alternative to peddling deceit.
BMJ Rapid Response Letters, March 2006
Reply to: Jorgensen KJ, Gotzsche PC. Content of invitations for publicly funded screening mammography. BMJ 2006;332;538-41.

Penston J.
The real challenge to the medical profession.
BMJ Rapid Response Letters, June 2006
Reply to: Hutchinson L. Challenges of training doctors in the new English NHS. BMJ 2006;332;1502-6.

Penston J.
An ill use of words…
BMJ Rapid Response Letters, July 2006
Reply to: Du Toit J, Hamilton W, Barraclough K. Risk in primary care of colorectal cancer from new onset rectal bleeding: 10 year prospective study. BMJ 2006;333;69-70.

Penston J.
So, nurses and doctors are not the same after all.
BMJ Rapid Response Letters, July 2006
Reply to: Bramwell R, West H, Salmon P. health professionals’ and service users’ interpretation of screening test results: experimental study. BMJ, doi:10.1136/bmj.38884.663102.AE (published 13th July 2006)

Penston J.
The rights of angels…
BMJ Rapid Response Letters, July 2006
Reply to: Salvage J. Nurses get a tongue lashing. BMJ 2006;333;265.

Penston J.
P-values without value?
BMJ Rapid Response Letters, August 2006
Reply to: Gotzsche P. Believability of relative risks and odds ratios in abstracts: cross sectional study. BMJ 2006;333;231-4.

Penston J.
Clearing the ground for common sense.
BMJ Rapid Response Letters, September 2006
Reply to: Bianchi MT & Alexander BM. Evidence based diagnosis: does the language reflect the theory? BMJ 2006;333;442-5.

Penston J.
The intolerant streak in current medical education…
BMJ Rapid Response Letters, September 2006
Reply to: Kmietowicz Z. Keeping Paice with reforms. BMJ 2006;333;518

Penston J.
An enlightening analogy.
BMJ Rapid Response Letters, November 2006
Reply to: Links M. Analogies between reading of medical and religious texts. BMJ 2006;333;1068-70.

Penston J.
A textbook case of cherry-picking.
BMJ Rapid Response Letters, November 2006
Reply to: Wald DS, Morris JK, Law M, Wald NJ. Folic acid, homocyteine, and cardiovascular disease: judging causality in the face of inconclusive trial evidence. BMJ 2006;333;1114-7.

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